European Journal of Cardiovascular Medicine

Background: Acute  pancreatitis  is  a  common  cause  of  acute  abdomen  in  pregnant  women Acute pancreatitis in pregnancy (APIP) is rare and occurs in  approximately 1 in 1000 to 1 in 4000  births. The most common symptom of acute pancreatitis is epigastric pain radiating to the back which is accompanied by nausea, vomiting and fever. Aims and objectives: The present study was done to evaluate the maternal and perinatal outcome of acute pancreatitis during pregnancy. Methods: The present study was hospital based retrospective observational study. A total of thirty-eight patients were admitted with acute pancreatitis complicating pregnancy between January 2020 to December 2020 in the department of Obstetrics and Gynaecology in IPGMER and SSKM Hospital, West Bengal, India and were followed up until after delivery. Statistical data were analysed by using Microsoft Excel and SPSS V.20 software. Results: Incidence of acute pancreatitis in our study was 38 in 11,899. Maximum gestational age was 36 weeks i.e. 10 (26.3%) followed by 30 weeks 6 (15.8%). Among causes of acute pancreatitis Idiopathic was 12 (31.6%) followed by gallbladder stone 8 (21.1%), fatty lever and obesity were 4 (10.5%) each, trauma was 3 (7.9%). Raised S Amylase level was 33 (86.38%) and raised S Lipase level was 17 (44.7%), which is statistically significant. HELLP syndrome was present in 3 (7.9%) cases. In maternal complications Jaundice and loss off weight was observed in 5 (13.2%) cases each. Sepsis was present in 3 (7.9%) cases. Term deliveries were observed in 21 (55.2%) cases, miscarriage and still born was seen in 4 (10.5%) cases each. Babies delivered at 34 weeks, 36 weeks and IUFD was present in 2 (5.3%) cases each. Conclusion: The course of acute pancreatitis in pregnancy is usually mild and self-limiting. But, it can be rapidly progressive and fulminant with complications like electrolyte imbalance, ARDS and DIC. Most patients delivered preterm. Conservative management till delivery by multidisciplinary team lead to good maternal and perinatal outcome.