ackground: This study examines the role of medical and socio-environmental factors in congestive heart failure (CHF) readmissions, seeking to mitigate the economic and societal burdens associated with hospital readmission of CHF patients. Methods: An observational descriptive cross-sectional study was taken at the Department of Cardiology, Bangabandhu Sheikh Mujib Medical University in Dhaka, spanning from May 2016 to April 2017. The study included 102 patients with congestive heart failure (CHF) who had previously been hospitalized for the condition. Their comprehensive medical records were meticulously reviewed, and the data was gathered by analyzing laboratory test results, electrocardiograms, and echocardiograms. Results: The study included 68 male participants and 34 female participants, with an average age of 55 years (±14). Factors associated with readmission included older age (p < 0.0004), residence in urban areas (p<.001), limited education retired status (p<.05), middle-class income (61.8%), smoking history, demotivation leading to medication discontinuation (p < 0.008), family caregiver presence (p<.05), partial adherence to diet (72.5%), partial or non-adherence to drugs (p < 0.004), lack of adherence to lifestyle (55.9%), absence of immunization against influenza/pneumococcus (91.2%), inadequate self-care management education (68%), and no discharge plan (59%). Medical factors included co- morbidities (98%), with depression (59%) being the most common, followed by anemia (58%), renal dysfunction (44%), diabetes (41%), hypertension (36%), and hypothyroidism (22%). Infections (19%) and worsening heart failure (64%) were also observed. Conclusion: Hospital readmission risk in CHF patients is influenced by a complex interplay of demographic, socio-environmental, and medical factors. Addressing these factors comprehensively can reduce or prevent subsequent readmissions, improving patient outcomes and reducing healthcare costs.