European Journal of Cardiovascular Medicine

Background:  Worldwide, the incidence of human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV) is on high alert. Both viruses' route of transmission is similar; can lead to chronic disease, cancer and death, patients affected by these viruses face detrimental side effects to pathogenicity of viruses and even to antiviral agents. Our study is focused on the study of HIV and HBV co-infections among patients attending a tertiary care hospital. Materials and Methods: This is a retrospective study done in the Department of Microbiology, ACSR Medical College from January 2020 to April 2023.  HIV were tested by using 3rd & 4^th generation ELISA kits as per NACO guidelines, further testing of duplicates was done by HIV rapid kits of two different principles. Hepatitis B surface antigen (HBsAg) were tested by 3rd generation ELISA kits. All positive samples are usually reconfirmed with repeat samples. Results: HIV and HBV coinfection was noted in 0.5% of the tested population. Age wise distribution of HIV and HBV dual infection cases were observed which shows 31-40 years age group patients were majorly affected by co-infection by these viruses. Male predominance was noted in the study population (Table 1), it was 70.83% of males. Conclusion: Screening of blood donors is mandatory to detect major viruses. As a result spreading of transfusion transmissible infections can be decreased in the community and to physicians. Early detection with new commercially available kits made it easy for detection of these viruses.