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Research Article | Volume 13 Issue:4 (, 2023) | Pages 1403 - 1409
A Study of Clinical Profile in Patients with Non Alcoholic Fatty Liver Disease in a Tertiary Care Hospital
1
1Intern, Nimra Institute of Medical Sciences, Vijayawada, Andhra Pradesh 2,3,4Intern, Alluri Sitarama Raju Academy of Medical Sciences, Eluru, Andhra Pradesh.
Under a Creative Commons license
Open Access
Received
Oct. 5, 2023
Revised
Nov. 9, 2023
Accepted
Dec. 15, 2023
Published
Dec. 28, 2023
Abstract

Non-alcoholic fatty liver disease (NAFLD), which affects 15–40% of the general population, is currently thought to be the most prevalent liver condition in the western world.1 An important contributor to liver-related morbidity and mortality is non-alcoholic fatty liver disease, which is becoming more widely known.2,3 Interest in this condition is growing among academics and clinicians in the relevant basic and clinical science domains due to its potential to progress to cirrhosis and liver failure. Objectives: To assess the clinical and biochemical profile of NAFLD cases. Material & Methods: Hospital based retrospective observational study was conducted in the Department of General Medicine over a Period 1 year. The cases for the study were selected retrospectively who were diagnosed as fatty liver by ultrasound imaging who attended the Department of General medicine. Study consisted of a total of 50 subjects. BMI was calculated as a measure of obesity. After an over-night fast, serum samples were obtained from all subjects for liver function tests, fasting blood glucose (FBS) serum insulin level. Results: FBG > 126 found in 4 patients (8%). OGTT > 200 found in 6 patients (12%). Impaired FBG was present in 9 patients (18%). Impaired OGTT in 11 patients (22%). Overall, diabetes was present in 8 patients (16%). Mild fatty liver is seen in 39 patients (78%). Moderate fatty liver is seen in10 (20%). Severe fatty liver is seen in 1(2%). Conclusion: Early detection, as well as steps to prevent the condition through lifestyle modification may halt the progression of a benign disease to an advanced illness. It is important for physicians and general practitioners to be aware of the clinical, biochemical, and histological profile of IDNAFLD which is such a common liver disorder.

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