European Journal of Cardiovascular Medicine

Introduction: Stroke is one of the leading causes of mortality and long-term disability in both developed and developing countries. Aim: To establish relationship of Homocysteine level in patients of acute brain stroke event. Methods: This study was a Observational–comparative study on 30 cases and 30 controls aged above 18 years conducted at the General Medicine department of Sawai Maan Singh Hospital and attached group of Hospitals from Feb 2020 to jan 2021. Blood samples would be drawn for serum homocysteine, vitamin B12 and folate level. Compare the different outcome of brainstroke with different values of homocysteine. Results: Difference in age, sex and residence of cases and controls was found to be statistically insignificant. mean homocysteine level in cases was 18.55±7.99 which was higher compared to mean homocysteine level of controls 12.17±4.86(p value<0.05). Conclusion: Homocysteine level in blood was higher among cases of acute brain stroke in absence of traditional risk factors. It should be considered as independent risk factor for stroke.