European Journal of Cardiovascular Medicine

Background: The issue of organophosphorus (OP) poisoning remains a significant global health concern, especially prevalent in developing nations. Aims and Objective: This current investigation endeavors to examine the clinic-demographic characteristics observed among patients exhibiting symptoms of OP poisoning. Methodology: A retrospective and prospective study spanning a duration of one and half year was carried out on patients with OP poisoning at a tertiary-level medical college. Results: Throughout the study duration, a total of 40 patients presented themselves. Instances of intentional self-poisoning (95%) outweighed those of accidental exposure (5%). The preponderance of patients were identified as housewives (32.5%), succeeded by individuals in occupations such as private job, farmers, studentship, sweepers and some were unemployed (5%). Among the toxins ingested by patients, Dichlorvas (42.5%) emerged as the predominant choice (35.74%), trailed by Chlorpyrifos, Dimethoate, Methyl parathion, Phorate , Thiomate and Monocrotophos. Manifestations of nausea and vomiting, observed in 85.02% of cases, while the predominant sign was miosis, noted in 91.94%. The mean duration of hospital stays varied among the different severity level. In terms of outcomes, 75% of patients survived without the need for mechanical ventilation and the mortality rate documented in our study stood at 10%. Conclusion: The current investigation revealed that a significant proportion of the patient cohort consisted of individuals in their youthful years, with males surpassing females in representation. Deliberate poisoning incidents exceeded accidental ones.