European Journal of Cardiovascular Medicine

Background: India has now become the diabetic capital of the world, with over 30 million diabetic individuals. Cardiac involvement in diabetes commonly manifest as coronary artery disease. Invasive diagnostic modality like Coronary Angiography serves as a diagnostic as well as therapeutic aid in the management of coronary artery disease and it remains the gold standard technique. Objectives: Present study is an attempt to find out how coronary artery involvement in diabetics differs from that of non-diabetics with special interest in their electro-cardiography and angiographic profile.  Methodology: 50 patients having acute coronary syndrome undergoing coronary angiography, aged 18-60 years, were included in present study, and grouped into 2; group A having diabetes (n=25) and group B without diabetes (n=25). Angiographic extent, type of vessel, number of vessels, severity involving coronary artery and its branches in patients with acute coronary syndrome (ACS) were studied and compared in both groups. RESULTS: Significantly higher differences in age, sedentary lifestyle, and hypertension were seen among diabetics than non-diabetics. Significantly higher diabetic cases had ST-T changes. Diabetic patients had more multivessel, multi-lesion, extensive and small vessel disease than nondiabetic patients.  Conclusion: According to the present study, severe forms of coronary artery lesions were found common among diabetic patients as compared to non-diabetic patients.