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Research Article | Volume 13 Issue:4 (, 2023) | Pages 678 - 680
Hereditary Angioedema with C1 Inhibitor (C1-INH) Deficiency: A Case Series
Under a Creative Commons license
Open Access
Received
Sept. 19, 2023
Revised
Oct. 3, 2023
Accepted
Oct. 23, 2023
Published
Nov. 13, 2023
Abstract

Hereditary angioedema (HAE) is an autosomal dominant disease due to C1 esterase inhibitor deficiency (C1-INH). Patients present with non-pruritic subcutaneous and sub mucosal edema in the absence of urticaria in the first or second decade of life. Even though the disease causes significant morbidity and mortality, the diagnosis is often late or even completely missed. Diagnosis of HAE is made by assessing C1-INH levels in blood. In a populated country like India, the disease prevalence would be high. This case series emphasizes the importance of early diagnosis and prompt treatment of a potentially fatal disease.

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