European Journal of Cardiovascular Medicine

Introduction: Thyroid hormones are not essential for maintenance of vital functions of life, their deficiency causes severe deficit in mental and physical growth and extreme decrease in body metabolism. Aim: To study nerve conduction parameters in primary hypothyroidism patients. Method: study conducted on 84 patients( 42 patients in each  case group and control group) aged between 20 to 45 years at Department of Medicine, S.M.S. Medical Collage, Jaipur, Rajasthan from May 2020 onwards for one year or till the sample size was achieved and two months for data compilation and analysis. Cases and control fulfilling inclusion and exclusion criteria were taken into study. The study access nerve conduction parameters in primary hypothyroidism patients. Result: mean age for case group was 38.09 years and for control group it was 34.9 years( p >0.05). There was significant difference seen inFT3, FT4, TSH and anti TPO test. Significant difference in FT3 in abnormal nerve conduction and normal nerve conduction patients, FT4, TSH and anti TPO was found non-significant in abnormal nerve conduction and normal nerve conduction patients. Conclusion: Performing electrophysiological studies early in the course of the disease in hypothyroid patients is suggested, in order to detect nervous system involvement.