European Journal of Cardiovascular Medicine

Introduction Diabetes mellitus affects > 530 million individuals across the globe and is responsible for most of the world’s burden of preventable blindness, end-stage renal disease, and non-traumatic lower limb extremity amputation. Diabetic kidney disease was traditionally considered to be caused by adverse effects of increased levels of glucose (metabolic theory). However multiple studies have found a low-grade inflammation in patients with diabetic kidney disease. Materials And Methods 119 Diabetic patients were selected for this study. Information is collected and detailed history is taken using pre-formed proforma at the time of admission. The diagnosis of T2DM was made according to the American Diabetes Association guidelines. The complete renal examination was applied to all participants, and the diagnosis of nephropathy was made by microalbuminuria and kidney size. Results Out of the 119 patients selected mean age of the study population was 56.65 +/- 9.67, 86 patients were diabetics without kidney disease and 33 were patients with diabetic kidney disease. The median neutrophil count in our study is 4545 in patients without DKD and in patients with DKD, it is 4862 which is statistically significant as the p-value is < 0.5. Conclusionour study sheds light on the association between the development of diabetic nephropathy. The neutrophil count is a good indicator of the risk of diabetic nephropathy and can be used as a predictor of diabetic nephropathy.