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Research Article | Volume 13 Issue:4 (, 2023) | Pages 432 - 436
Serum Cortisol Level as A Biomarker in Predicting the Severity of Stroke
Under a Creative Commons license
Open Access
Received
Oct. 16, 2023
Revised
Oct. 29, 2023
Accepted
Nov. 18, 2023
Published
Nov. 30, 2023
Abstract

Background: A number of clinical and radiological indicators can reliably detect the prognosis of a stroke. Improved biomarkers for predicting prognosis in acute ischemic and hemorrhagic stroke are still elusive. Aims and Objective: The present study was aimed to observe whether serum cortisol acts a biomarker in predicting the severity of stroke. Materials and Methods: A prospective study performed among 50 patients with ischemic in Group A and 50 patients with hemorrhagic stroke in Group B. The random serum cortisol of these patients was compared with the NIHHS score. Results: Incidence of hypertension was significantly higher in group B than group A (72% vs. 38%; P<0.0001). Both systolic and diastolic BP were significantly higher in group B in comparison to group A (P<0.001). Severity of stroke was significantly higher in group B in comparison to group A (P<0.001). Mean cortisol levels were significantly more in group B in comparison to group A (P<0.001). Also, a statistically significant correlation with raised serum cortisol levels and the severity of stroke irrespective of type of stroke was observed. Conclusion: The study revealed that serum cortisol can be used as a biomarker for the prediction of severity of stroke.

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