European Journal of Cardiovascular Medicine

Computed Tomography (CT) of the thorax plays a pivotal role in understanding the progression of COVID-19 pneumonia. This study aimed to analyze the spectrum and temporal progression of CT findings in COVID-19 patients. Methods: A prospective observational study was conducted on 246 COVID-19 positive patients from August 2020 to July 2021. A total of 288 CT scans were evaluated, with a focus on changes over time and their lobar distribution. Results: Ground Glass Opacities (GGOs) were the most common early finding, seen in 83.3% of patients within 0-4 days and decreasing to 35.29% after 21 days. The presence of GGOs with irregular lines and interfaces increased over time, peaking at 21.0% in the 15-21 day group. Lower lobes were predominantly involved, with the mean CT scores rising from 5 in the early phase to 14.53 in later stages, indicating increased disease severity. Pleural effusion and pneumothorax were noted in a minority of cases. Conclusion: The study provides detailed insights into the temporal radiological progression of COVID-19. The findings underscore the evolving nature of the disease's pulmonary manifestations and reinforce the necessity of serial CT scans for effective patient management.