Contents
Download PDF
pdf Download XML
362 Views
134 Downloads
Share this article
Research Article | Volume 13 Issue:3 (, 2023) | Pages 1048 - 1052
Study of the Apolipoprotein B/ Apolipoprotein A1 Ratio as a Potential Marker of Plasma Atherogenicity in Acute Myocardial Infarction (STEMI)
Under a Creative Commons license
Open Access
Received
June 30, 2023
Revised
July 15, 2023
Accepted
July 28, 2023
Published
Aug. 11, 2023
Abstract

Background: The apolipoprotein B (ApoB) is the main component of very low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), low-density lipoproteins (LDL) and lipoprotein(a) (Lp(a)) particles. LDL contains variable quantities of cholesterol, but each lipoprotein contains a single ApoB protein, while Apolipoprotein A1 (ApoA1) is the main apolipoprotein incorporated into high‐density lipoprotein (HDL). It has a major role in reversing cholesterol flow and cellular cholesterol homeostasis once detected. Therefore, the ApoB/ApoA1 ratio reflects the cholesterol balance between atherogenic and anti-atherogenic lipoprotein particles. Aim: The aim of the study is to measure ApoB/ApoA1 ratio in patients with acute myocardial infarction. Methods: Total of 60 patients aged 18–80 years were included in the study. The plasma levels of total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), apolipoprotein A1, ApoB protein, ApoB/ApoA1 ratio were determined after a 12 h fasting period. Results: Mean ApoB/ApoA1 ratio for our study was 0.87 with 60% of STEMI patients had ratio >0.8. In our study, 23.64% of patients had absolutely normal lipid profile with deranged ApoB/ApoA1 ratio. Conclusion: Despite normolipidemic, the subjects with the unfavourable ApoB/ApoA1 ratio had more atherogenic lipid profile and corelated its relationship with the severity of CAD.

Keywords
Recommended Articles
Research Article
Study the effects of obesity on blood glucose levels in adolescents in Central Uttar Pradesh - An observational cross - sectional study
...
Published: 11/09/2025
Download PDF
Research Article
Evaluation of Ultrasonographic Strain Elastography in Differentiating Benign and Malignant Thyroid Nodules: A Histopathology-Correlated Study
Published: 11/09/2025
Download PDF
Research Article
Sugammadex Versus Neostigmine for Reversal of Rocuronium Block: Recovery Profile and Adverse Events- A Comparative Study
Published: 11/09/2025
Download PDF
Research Article
Prevalence and Associated Factors of Dysmenorrhea among College-Going Girls in Jhalawar District, Rajasthan
...
Published: 11/09/2025
Download PDF
Chat on WhatsApp
Copyright © EJCM Publisher. All Rights Reserved.