Contents
Download PDF
pdf Download XML
324 Views
112 Downloads
Share this article
Research Article | Volume 13 Issue:4 (, 2023) | Pages 656 - 660
The Function of Nt-Probnp in Diastolic Heart Failure Diagnosis and Its Relationship with Echocardiography
Under a Creative Commons license
Open Access
Received
Sept. 19, 2023
Revised
Oct. 3, 2023
Accepted
Oct. 23, 2023
Published
Nov. 13, 2023
Abstract

Background and Aim: Diastolic heart failure is a common yet difficult to identify condition. The study's goal was to investigate and link NT-proBNP levels with four classes (grade I to grade IV) of diastolic dysfunction as measured by echocardiography. All patients underwent a thorough clinical examination, blood biochemistry, electrocardiography, chest X-ray, echocardiography, and plasma NT-proBNP testing. Material and Methods: The current study was carried out on 50 DHF patients enrolled from outdoor and indoor patients in the Department of Medicine, Tertiary Care Teaching Institute of India over a one-year period. Clinical assessment and echocardiography were performed on the patients. The autoanalyzer was used to estimate NT-proBNP utilising the electrochemiluminisense method. Echocardiography was used to classify patients into different levels of diastolic dysfunction. Results: The mean levels of NTproBNP in individuals with systemic hypertension were statistically significant (p0.05) higher than in non-hypertensive patients in the current investigation. NT-proBNP levels were observed to be statistically greater in LVH participants compared to those without LVH. (p≤0.05) In the current study of 50 patients with diastolic heart failure, 36 patients (72%) had grade I diastolic dysfunction, 9 patients (18%) had grade II diastolic dysfunction, 3 patients (6%) had a grade III diastolic dysfunction, and 2 patients (3%) had a grade IV diastolic dysfunction. Conclusion: Serum NT-proBNP levels give reliable diagnostic accuracy for detecting diastolic heart failure, and they correlate well with increasing degree of diastolic dysfunction as measured by a well-established modality of echocardiography. In symptomatic individuals, NT-proBNP can accurately detect the presence of isolated diastolic dysfunction and is a valuable diagnostic for ruling out patients with impaired exercise tolerance of non-cardiac origin.

Keywords
Recommended Articles
Research Article
Study The Effects of Dexmedetomidine on Postoperative Nausea and Vomiting. And Adverse Effects Like Bradycardia and Hypotension In Patients Undergoing Laparoscopic Surgeries
...
Published: 30/01/2025
Download PDF
Research Article
Study the hemodynamic parameters of Dexmedetomidine and Tramadol
...
Published: 30/09/2025
Download PDF
Research Article
Study the efficacy of dexmedetomidine for attenuation of hemodynamic responses in patients undergoing laparoscopic surgeries
...
Published: 30/12/2024
Download PDF
Research Article
Compare The Postoperative Analgesia and Adverse Effects of Bupivacaine in Comparison to Bupivacaine and Nalbuphine Combination During Spinal Anesthesia in Lower Abdominal Surgeries
...
Published: 30/09/2025
Download PDF
Chat on WhatsApp
Copyright © EJCM Publisher. All Rights Reserved.