European Journal of Cardiovascular Medicine

Introduction and Background: Since it is the second most frequent cancer in males, and the second leading cause of cancer-related death, prostate cancer is a key focus of healthcare research and development. Traditional methods of assessing prostate cancer relied on digital rectal examinations and PSA levels because of the prostate's inconvenient position. Material and Methods: 20 patients with high PSA levels and aberrant DRE results who were sent to our clinic were analyzed. From December 2021 to November 2022, at Mahavir institute of Medical Sciences, Vikarabad, Telangana, researchers gathered data. All patients provided informed consent after having potential biopsy consequences outlined to them. Antibiotics were provided as a preventative measure before the operation.  Results: In our prospective study, 20 patients with abnormal digital rectal examination and elevated PSA levels underwent transrectal real-time strain elastography, transrectal ultrasonography, a systematic 12-core biopsy, and additional targeted biopsies from abnormal areas found by transrectal real-time strain elastography and transrectal ultrasound. The interpretations from each of these techniques were contrasted with the histopathological diagnosis. Conclusion: This research shows that compared to ultrasonography, elastography is more sensitive to the presence of malignancies and has a strong negative predictive value, both of which aid in avoiding unnecessary biopsies. Elastography and ultrasonography together improve cancer detection by pinpointing malignant tumors and facilitating guided biopsies.