Intramyocardial Stem Cell Transplantation in Cardiac Surgery: From Preclinical Backgrounds to the PERFECT trial

doi:10.5083/ejcm.20424884.04.03

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Review Article | Volume:1 Issue 4: (, 2011) | Pages 21 - 30

Intramyocardial Stem Cell Transplantation in Cardiac Surgery: From Preclinical Backgrounds to the PERFECT trial

Peter Donndorf, MD

Under a Creative Commons license

Open Access

DOI : 10.5083/ejcm.20424884.04.03

Published

Dec. 25, 2010

Abstract

gery and interventional cardiology for almost one decade. With preclinical studies showing prom- today in the setting of ischemic heart disease has been rather modest. However, clinical studies per- completion of ongoing phase III trials is mandatory. The following article repeats preclinical and clinical prerequisites for cardiac stem cell application and introduces the German Phase III PERindo- pril Function of the Endothelium in Coronary artery disease Trial (PERFECT) for intramyocardial stem cell injection in combination with CABG surgery.

Keywords

Intramyocardial

Stem Cell

European Journal of Cardiovascular Medicine

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