European Journal of Cardiovascular Medicine

Background: Acne scarring commonly seen in young adults causes marked psychological distress. Commonly used procedural treatments for post‑acne scarring have limited efficacy. This prospective, randomized study was undertaken to evaluate the efficacy and adverse effects offractional CO2 laser, microneedling, and platelet‑rich plasma (PRP) in post‑acne scarring. Materials and methods: This are a prospective, descriptive and hospital-based study. Total of 140 cases were enrolled in study carried out for 1 year in the Department of Dermatology at tertiary health centre and medical college with subsequent follow up of up to six months. Prior to the study, an institutional ethical committee clearance was obtained. Patients with acne scars under the groupings of a score > 3 points on Global Acne Scarring Classification Scale were enrolled. Result: Out of 70 patients treated with fractional CO2 laser, 01 patients had satisfactory response i.e. 1.4% improvement in point score, majority of patients had very good response 36 i.e. 51.5% improvement in point score, 26 patients were in the good response category 37.1% improvement in point score) and patients had excellent results. The objective score was calculated for derma roller therapy, and the results indicated that the baseline mean objective score which was 28.99±2.20 was reduced to 18.85±1.85 after the treatment. This difference was found to be highly significant with p value as 0.000. The reduction in the objective scores was found to be 39.69% Conclusion: Fractional Co2 laser resurfacing is more efficacious than micro needling with longer down time interfering with daily activity of patients and mandatory avoidance of sun exposure in post treatment period are the limiting factors