Introduction: We done the Comparative Assessment of Motor Nerve Conduction Velocity among Non-Diabetic, Diabetic Non-Smoker and Sub Groups of Diabetic Smoker the diagnosis of diabetic peripheral europathy is mainly based on its characteristic symptoms, but mostly these symptoms develop at any stage of neuropathic impairment or they may not develop at all. Materials and Methods: Smoking index is used to find the exposure of smoking on body quantitatively and is calculated by multiplying the average number of cigarettes smoked per day in last seven days with the duration of smoking in years