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Research Article | Volume 12 Issue :4 (, 2022) | Pages 153 - 157
Umbilical Cord Albumin as Predictive Factors for Hyperbilirubinemia in Term Neonates
Under a Creative Commons license
Open Access
DOI : 10.5083/ejcm
Published
Dec. 29, 2022
Abstract

Background: Neonatal hyperbilirubinemia is a frequent illness that occurs in newborns during their first week of life. Due to social reasons, such as an early naming ceremony, the risk of nosocomial infections, and financial constraints, early discharge of healthy term neonates is a typical practice. Neonatal hyperbilirubinemia is the most frequent reason for readmission in a sizeable number of neonates. Early discharge of healthy term neonates is a worry because there have been reports of bilirubin-induced brain injury and its sequelae, like kernicterus. Early hyperbilirubinemia detection in neonates is crucial, for this reason. Aims and Objective: To study the efficacy of cord blood albumin as a predictor of neonatal jaundice and to study their association with significant hyperbilirubinemia requiring further intervention. Materials and methods: The prospective study conducted in Department of Pediatrics at Rajshree Medical & Research Institute, between 15 January 2021 to 14 January 2022. Cord blood was sent for albumin analysis and fourth day venous sample was sent for serum bilirubin and blood group analysis. Results: This study enrolled 119 term neonates. Out of which 15 neonates had albumin level less than 2.9mg/dl, 61 neonates between 2.9mg/dl-3.3mg/dl and 43 neonates above 3.4mg/dl. Out of total study subject enrolled 11.8% required intervention like phototherapy. Conclusion: From this study, cord blood albumin level was demonstrated as predictive marker for neonatal hyperbilirubinemia with a sensitivity of 60%

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