Introduction: The brain is normally a sterile site that is protected from infection by specialized barriers, including the bony skull and the blood-brain barrier. Consequently, infections of the central nervous system are comparatively rare. Material and Methods: This study was starting from January of 2022 to the November 2022, researchers was collected data in a cross-sectional fashion. This research was conducted at the Department of Microbiology at the Ayaan Institute of Medical Sciences in Moinabad, Telangana. Results: This research shown that brain abscesses might manifest at any age. The most vulnerable age range was between 11 and 20. Nonetheless, the peak incidence rate was between the ages of 30 and 40. Incidence of this condition occurs between the ages of 30 and 50. According to Sinha et al., 74.89% of their patients were younger than 20. Conclusion: In addition, treating this cluster of risk factors would be more effective if more people knew about the devastating consequences of infections of the scalp, cheeks, ears, and paranasal sinuses. Cyanotic congenital heart disease patients who have not undergone surgery would benefit greatly from a high index of clinical suspicion coupled with prompt treatment