Background: Testicular lesions encompass a wide range of pathological conditions, including inflammatory, neoplastic, and developmental disorders. This study aims to provide an overview of the histopathological spectrum of testicular lesions observed at Amruth diagnostic laboratory. Methods: A retrospective analysis was conducted on testicular specimens received at Amruth diagnostic laboratory over a four-year period. Relevant clinical and pathological data were collected from the medical records, including age, presenting symptoms, and histopathological findings. The specimens were examined microscopically, and diagnosis was made based on established criteria. Results: A total of 200 testicular specimens were included in the study. The age of the patients ranged from 18 to 75 years, with a mean age of 42 years. The most common presenting symptom was testicular pain, reported in 65% of cases. The histopathological analysis revealed a diverse range of testicular lesions. Inflammatory conditions such as orchitis and epididymo-orchitis were observed in 20% of cases, followed by testicular tumors, including germ cell tumors (70%), sex cord-stromal tumors (12.5%), and metastatic tumors (7.5%). Additionally, non-neoplastic lesions like testicular atrophy, interstitial fibrosis, and vascular disorders were identified in 7.5% of cases. These findings provide important insights into the histopathological spectrum of testicular lesions in our study population. Conclusion: This study provides insights into the histopathological spectrum of testicular lesions encountered at Amruth diagnostic laboratory. The findings highlight the importance of a thorough histopathological evaluation in diagnosing and managing various testicular conditions. Understanding the diversity of testicular lesions can aid in appropriate treatment planning and counselling for patients with testicular pathologies. Further research and prospective studies are warranted to validate these findings and explore potential risk factors associated with specific testicular lesions. |