European Journal of Cardiovascular Medicine

Background: The most prevalent cause of hair loss in men is androgenetic alopecia (AGA), which has few available treatments. One of the more recent treatment options for the management of AGA that has produced encouraging outcomes is platelet-rich plasma (PRP) therapy. Aims and Objectives- the efficacy of PRP versus topical 10% minoxidil and microneedling in the treatment of androgenic alopecia and study the safety profile of these modalities. Materials and Methods: A prospective study was conducted in Department of Dermatology, Dr SN Medical College Jodhpur, 90 male patients with grade III to VI were randomly divided in three groups. Group 1: Platelet Rich Plasma. Group 2: 10% Minoxidil. Group 3: Microneedling. Results: The mean patient age in the current study was 36.03 years for PRP, 33.56 years for Minoxidil, and 35.9 years for the microneedling group. The mean hair thickness increased by 2.26 micron in PRP group, 8.76 micron in minoxidil group and 1.77 micron in micro needling group. The mean hair density of the patients in all groups increased statistically significantly. Conclusion- Overall, PRP can be considered an effective modality to begin treatment in patients to be supplemented with minoxidil if hair loss progresses. Microneedling can be used as a lone modality in patients or an additive therapy with PRP. In addition to its own action, it would help promote penetration of other therapeutic agents. Combining the following therapies can stimulate hair growth and halt hairloss for a while. These are effective before hair transplant surgery