Introduction:Lower end of the esophagus portosystemic anastomosis formed by Left gastric vein and Esophageal tributaries of accessory hemizygous vein. Although all these vessels contribute to the shunting of esophageal collaterals or varices, are the most important clinically, because of their predilection to bleeding. Sclerotherapy is associated with a wide range of complications ranging from transient pyrexia to esophageal perforation resulting in death. Complications following sclerotherapy depends on a number of factors namely nature of sclerosant used, amount of sclerosant, injection site, concentration of the drug and the time interval between the sessions. Material And Methods: A prospective and observation study on management of esophageal varices by endoscopic injection sclerotherapy using absolute alcohol as sclerosant has been done in Endoscopy Unit.