European Journal of Cardiovascular Medicine

Background: To treat coronary artery disease, PCI is a well-established method. Its efficacy in treating symptoms is widely known. In patients with baseline intact left ventricular function, the impact of PCI on systolic and diastolic function is uncertain. We postulated that individuals with chronic stable angina may have impaired regional contractile performance and that PCI would have the potential to enhance ventricular systolic and diastolic function following successful coronary angioplasty. Methods: The diagnosis of CSA was made based on the history of exertional substernal chest discomfort suggestive of typical angina, physical examination, ECG changes, and 2D Echo features. Coronary angiography was performed after taking consent and PCI was performed based on the results of coronary angiography if deemed appropriate based on the existing guidelines. Patients with a SYNTAX score >22 on CAG were referred to undergo CABG. All patients were kept under follow-up and assessed for symptomatic improvement of chest pain and echocardiography along with tissue Doppler analysis was performed on day 1 and 6 weeks after PCI. Results: In this study, overall there is an insignificant improvement in trans-mitral E wave velocity compared to baseline value and 6 weeks after PCI with a p-value of 0.8. Trans-tricuspid E wave velocity also showed an insignificant (p=0.5) improvement 6 weeks after PCI. Trans mitral and trans-tricuspid late diastolic filling velocities also showed an insignificant improvement 6 weeks after PCI with a p-value of 0.4 and 0.6 respectively. Deceleration times of the E waves across mitral and tricuspid valves did not improve significantly after PCI. Conclusion: The study showed conventional echocardiographic parameters of mitral and tricuspid diastolic flow patterns failed to show significantly, the impact of PCI on myocardial function. Tissue Doppler parameters of myocardial systolic and diastolic function across the mitral and tricuspid valves were able to show a significant improvement in myocardial function soon after PCI and this persisted till 6 weeks after PCI