Background: Anal fissure which is defined as a longitudinal tear in anoderm under the dentate line is one of the most common benign diseases of anorectal area, and due to the severe pain during the defecation and emotional stress that it causes may reduce people’s quality of life. There are several treatment methods such as medical and surgical procedures. Objective: To determine the effectiveness of lateral internal sphincterotomy in the treatment of chronic anal fissures resistant to pharmacological treatment in terms of pain, healing, complications, recurrences and patients satisfaction Methods: This study includes retrospective analysis of 100 patients (male 71 and female 29) who underwent lateral internal sphinceterotomy for the treatment of chronic anal fissure between september 2020 to october 2022 for a period of about two years. All these patients were operated under general or spinal anesthesia after obtaining consent and routine examinations. We analysed the patients clinical features, complications and outcomes of Lateral internal sphincterotomy Results: As a result the final analysis included 70 were male patients and 29 were female patients with mean age of 38 years, age ranged between 18-56 years, 89% presented with pain, 45% bleeding per rectum ,37% constipation , 32% complain of hard stool, 26% had sentinel pile and 54% were having an increase anal tone. Bleeding per rectum was common problem in 34% patients in early post operative period followed by 3% perianal abscess, 2% perianal hematoma, 7% had incontinence of flatus followed by 2% liquid stool incontinence and 1% solid stool incontinence all patients with flatus and liquid stool incontinence regressed with conservative management. Recurrence occurred in 4% patients, nearly complete healing occur in 95% patients and 91% patients had no complain regarding pain: Conclusion Lateral internal sphincterotomy is a safe, effective, and inexpensive procedure that leads to quick symptomatic improvement and healing in chronic anal fissure with minimal complications