European Journal of Cardiovascular Medicine

Background: Cluster of obesity, dyslipidemia, hypertension and impaired glucose metabolism is the foundation of metabolic syndrome. Its prevalence has been on rise in India due to socioeconomic transitions. The aim of this study is to analyze thyroid hormone function in cases with metabolic syndrome. Method: It was cross sectional case control study. In this study 100 cases with metabolic syndrome and 100 normal individuals were enrolled.  Result: Total 68% of cases with metabolic syndrome were Euthyroid, 6% cases had hypothyroidism, 20% cases had sub-clinical hypothyroidism and 6% cases had hyperthyroidism. High waist circumference was present in 91.17% of euthyroid cases, 90% of subclinical hypothyroid cases, 83.33% of hypothyroid cases and 100 % of hyperthyroid cases. Increased serum triglyceride levels were present in 69.11% of euthyroid cases, 60% of subclinical hypothyroid cases, and 83.33% of both hypothyroid and hyperthyroid cases.50% of Euthyroid cases were hypertensive while 100% cases of sub-clinical hypothyroidism, hypothyroidism and hyperthyroidism were hypertensive. Increased serum HDL was found in 60.29% of euthyroid cases, 55% of subclinical hypothyroid cases, 66.66% and 33.33% of hyperthyroid cases. High fasting blood glucose was present in 70.58% of euthyroid cases, 90% of subclinical hypothyroid cases, 66.66% of hypothyroid cases and 83.33% of hyperthyroid cases. Conclusion: In our study one fifth of metabolic syndrome cases or every fifth case with metabolic syndrome had Sub-clinical hypothyroidism and one in every 16 cases had hypothyroidism.