European Journal of Cardiovascular Medicine

Introduction: Coronary artery calcification (CAC)  occurs  in  small  amounts  in  the early lesions of atherosclerosis  that  appear  in the second  and  third  decades of life, but it is found more frequently in advanced lesions and in older age. A positive CT study (defined as presence of any CAC) is nearly 100% specific for atheromatous coronary plaque. Since both obstructive and non- obstructive lesions can have calcification present in the intima, CAC is not specific for obstructive coronary disease. Aims: To compare CAC (coronary artery calcium) score in patients with Obstructive and Non-obstructive CAD, to compare CAC score in patients with single and multivessel disease, to compare CAC score in males and females, to compare CAC score in those with and without HT, Smoking and Diabetes and to compare CAC score between IRA and other vessels in multivessel disease. Materials and Methods: This study was conducted in the Department of NRS medical college, during the year January 2022 to December 2022.The study is a prospective observational non-interventional study involving 100 patients. Result: Men and women in the highest CAC score category showed an adjusted odd ratio for myocardial infarction of 7.7 (95%cl:4.1-14.5) and 6.7( 95%cl:2.4-19.1 ), respectively, compared with the lowest score category (0-100). The predictive power of CAC was independent of FRS category (low, intermediate or high). Conclusion: CAC scores showed good correlation in patients with obstructive CAD especially in Elderly, Diabetics and in those with a family history of CAD. There is less correlation of CAC score with regards to other conventional risk factors like Gender, Hypertension and Smoking in both obstructive and non-obstructive CAD.