Objective: The objective of this study was to analyze the histomorphological spectrum of kidney lesions observed in nephrectomy specimens at a tertiary care center. Methods: This retrospective study included a total of 200 nephrectomy specimens obtained from patients undergoing nephrectomy at a tertiary care center over a five-year period. The specimens were evaluated for histomorphological characteristics, including inflammatory lesions, cystic lesions, tumors, and other pathological findings. The data were analyzed using descriptive statistics. Results: Among the 200 nephrectomy specimens, various histomorphological lesions were identified. Inflammatory lesions were the most common findings, including pyelonephritis, glomerulonephritis, and interstitial nephritis. Cystic lesions were also frequently observed, such as simple renal cysts, polycystic kidney disease, and renal cystic neoplasms. Tumors accounted for a significant proportion of the specimens, with renal cell carcinoma being the most prevalent. Other pathological findings included vascular lesions, renal calculi, and congenital abnormalities. Conclusion: This study provides a comprehensive overview of the histomorphological spectrum of kidney lesions observed in nephrectomy specimens at a tertiary care center. The findings highlight the importance of accurate histopathological evaluation for the diagnosis and management of kidney diseases. Understanding the diverse range of kidney lesions is crucial for appropriate patient care and can aid in advancing our knowledge of renal pathology. |