European Journal of Cardiovascular Medicine

Background: Chronic Venous ulcer (CVU) is an ulcer on gaiter area persisting for more than six weeks and difficult to heal even after three months of treatment. The prevalence of CVU ranges from 0.18% and 1% and Standard therapy for CVU is multilayered bandages and treatment of incompetent veins to prevent recurrence. All adult patients having CVU, due to primary varicose veins were randomly allocated to two intervention groups (Group A- comprising of use of compression bandages along with treatment of varicose veins by Endovenous Laser ablation and Group B- Non usage of compression bandages after the aforesaid surgical intervention). Out of 60, total 30 (50%) cases were in each group. Quality of life and therapeutic outcomes were noted, and patients were followed for 6 months. Quality of life outcomes compared based on SF-36 questionnaire showed more improvement in group A in all 8 domains. Other parameters like use of analgesics, itching, eczema, and increased leisure activities were better with use of compression bandages. Healing of ulcer was faster in Group A. Charing Cross varicose vein questionnaire also showed more improvement in group A (p value<0.001, <0.001, 0.003   at 1 month, 3 month and 6 month, respectively). In chronic venous ulcer, four-layer compressive bandaging after surgery enhances the healing rate of venous  Dengue is an endemic disease in tropical and subtropical regions of the world causing severe epidemic in India and is endemic in many parts of India, especially in metropolitan cities and towns. There are evidences which states that platelet parameters may have diagnostic and prognostic value in febrile thrombocytopenia including Platelet count, Mean platelet volume (MPV), Platelet distribution width (PDW), Plateletcrit (PCT). These parameters are obtained as a part of Complete Blood Count using Automated Hematology analyzers. Aim and Objectives: of this prospective study is 1) To evaluate the role platelet parameters in Dengue fever and also to determine the relationship of platelet parameters with platelet count and disease severity. 2) to assess the utility of platelet profile in patients with Dengue fever and understand its significance so that adverse outcomes of this rapidly spreading disease can be controlled to a greater extent. Material and Methods: This study was conducted on 133 confirmed cases of Dengue infected patients for a period of 9 months from April 2022 to December 2022. The Platelet parameters like Platelet count, MPV, PDW and Plateletcrit were measured by using BC 300 plus Mindray Automated Hematology Analyzer on venous samples collected in K3EDTA from 133 patients and was compared with disease severity (DF/DHF/DSS) . These 133 patients were grouped into three according to platelet count (100000). Results: Out of 133 patients, 17 patients who had platelet count ulcer with better quality of life outcomes.