Background: Deep vein thrombosis (DVT) usually occurs when a blood clot (thrombus) forms in one or more of the deep veins. It can causes pain in leg or swelling. Sometimes there are subtle symptoms. Aim: This study was conducted to perform investigation of etiological variables, management strategies, and consequences among individuals presenting with DVT at a tertiary centre. Materials and Methods: The current study which was carried out over the course of three years at a tertiary care government hospital at Kurnool and it was prospective observational in design. Total 100 cases showed signs of deep vein thrombosis, and met the criteria for selection. Results: In present study average age was 40.2±17.9 years, with 26% of them falling between 30 and 40 years. The majority (21%) of individuals presented with discomfort and edoema but had no clear predisposing factors. Duplex venous ultrasound revealed that 57 (57%) had involvement of both proximal and distal veins, 40 (40%) cases had involvement of only proximal veins whereas only 3 (3%) had restricted involvement of distal veins. After 3 months, 81% of the patients had complete recovery. Recovery was observed in 62%, improvement in 18% and chronic changes were observed in 20% of the patients at end of 3 months in duplex venous ultrasonography. Conclusion: Young patients without any clear risk factors may develop and present with DVT, therefore factors that cause deep vein thrombosis in them are advised to be carefully assessed. A trustworthy non-invasive diagnostic tool is Duplex venous ultrasonography and is advised for clinically diagnosing and confirming DVT
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