European Journal of Cardiovascular Medicine

Background: Distal Peripheral Neuropathy (DPNP) is a frequent micro-vascular complication of long-term diabetes and one of the main causes of morbidity and disability due to ulceration and amputation. Our aim is Correlation Study of Peripheral Neuropathy in Impaired Glucose Tolerance and newly diagnosed Type-2 Diabetes Mellitus Methods: A prospective Cohort study was taken among 160 patients. From patients with diagnosis of Impaired Glucose Tolerance& Newly diagnosed case of Type -2 Diabetes Mellitus (DM) attending the OPD and IPD in Department of Medicine at our Medical Hospital. During study period from 1st of Feburary 2021 to 31st August 2022. Results: In the current study, the mean NDS for newly diagnosed diabetic participants was.43, whereas it was.30 for IGT subjects, and it was determined to be non-significant. In the current study, it was determined to be highly significant that the mean Sensory Nerve Conduction Velocity in newly diagnosed diabetes participants was 56.44± 9.85 and in IGT subjects it was 50.35± 10.94. Out of the total 160 study respondents, 32 subjects were having any kind of sensory abnormality in their body. out of these 32 subjects, 23 belongs to new diabetic group while nearly only 9 subjects belong to IGT group. This association was found to be significant with a p value 0.006 Conclusions: The mean Sensory Nerve Conduction Velocity in new diabetic subjects were 56.44± 9.85 and in IGT subjects were 50.35 ± 10.94which was found to be highly significant with a p value<0.001.However, The mean Sensory Nerve Action potential in new diabetic subjects were 7.64± 3.13 and in IGT subjects were 7.52 ± 3.24which was found to be non-significant with a p value 0.79.Patients with DM and pre diabetes are at elevated risk for PN, and PN patients are at increased risk for dm and pre diabetes