Background: The platelet count declines and petechiae appear in widespread distribution with spontaneous ecchymoses. Bleeding occurs at mucosal surfaces from the gastrointestinal tract and at venipuncture sites. Objective: to study Correlation between the laboratory features – thrombocytopenia, elevated hepatic enzymes, hyponatremia, high hematocrit and severity of dengue infection. Methods: It is an observational study conducted at a multispeciality teaching Hospital. The study population (cohort) was selected from the hospital inpatients who are admitted in paediatric intensive care unit as well as paediatric ward