European Journal of Cardiovascular Medicine

Introduction: Nephrotic syndrome, characterized by presence of heavy proteinuria, hypoalbuminemia, edema and hyperlipidemia, is a common renal disorder in pediatric population and is most common in Asian child.

Aims & Objectives: To know the bacterial etiologies and their antibiogram in urinary samples of Pediatricnephrotic syndrome.

Materials And Methods:   This was a Cross sectional, Descriptive study conducted for a period of 6 months i.e., January 2022 – June 2022 in pediatric patients admitted in PICU’s of KING GEORGE HOSPITAL, VISAKHAPATNAM.  Urine samples are collected and transported to Department of Microbiology, ANDHRA MEDICAL COLLEGE, VISAKHAPATNAM.

Results: Out of 70 urine samples studied, 21(30%) have urinary tract infection, 13(62%) were asymptomatic and 8(38%) are symptomatic.  Majority of UTI caused by E.coli 8(38%) followed by klebsiella 6(29%), Proteus 4(19%), Staphylococcus aureus 2(10%), Acinetobacter 1(4%).

Gram negative bacilli were sensitive to Amikacin, Cefixime, Piperacillin plus Tazobactum, Nirofurantoin, Meropenem.

Gram positive cocci were sensitive to Amoxicillin, Vancomycin, Linezolid.

Conclusion: Children with nephrotic syndrome are frequently predisposed to UTI and in most cases, it is asymptomatic.  It is necessary to examine the patient and prevent the risk of complications by initiating appropriate antibiotic therapy