Background: HIV is predominantly lymphotropic to CD4 (T-helper) lymphocytes Other cells bearing CD4 receptors are also infected (e.g, macrophages, B cells, Langerhans cells, NK cells etc.). Objective: To find out the various patterns and presentations of dermatological conditions occurring in HIV Patients and their association with CD4count. Methods: In this study we included 100 patients above age of 15 years who were infected with HIV Virus. Results: The most prevalent infection was candidiasisseen in 25 patients it was a definite maker for HIV disease progression and was seen in early as well as late stages of HIV infection. Dermatophytosis was the second most common fungal infection seen in 11patients. Among viral infections, herpes simplex virus(HSV) wasthemost common infection found in 12patients, Herpes zoster was seen in 8 patients. The most common non – infectious dermatosis seen in our study was seborrhoeic dermatitis in 12patients. Conclusions: Dermatological manifestations occur throughout the course of HIV infection some of the manifestations can be considered as the predictors of advanced immunosuppression.