European Journal of Cardiovascular Medicine

Introduction: Lactate dehydrogenase (LDH) is the enzyme which catalyzes the reversible conversion of locate to pyruvate. Since the reaction is an integral part of glycolytic pathway of carbohydrates metabolism, LDH is present in virtually all body tissues. There is increasing evidence that Endothelial cells and altered endothelial cells function to play an important role in the Pathogenesis of preeclampsia. Aims: To determine the relationship between serum concentrations of LDH and pre- eclampsia severity and LDH level in 3rd trimester of pregnancy with preeclampsia. Materials and Methods: The present study was a Observational Analytical Study. This Study was conducted from May 2021 to April 2022 at The study has done by Dept. of Biochemistry in collaboration with Department of Obstetrics and Gynecology, Burdwan Medical College and Hospital. Result:  We showed that, mean LDH was significantly higher in Case Group [526.4451± 66.8891 (IU/L)] compared to Control Group [236.1830± 24.1872 (IU/L)] (p<0.0001) and Weight was slightly higher in Control Group [61.8595± 4.5723 (Kg)] compared to [61.4261± 4.7520 (Kg)] Case Group but this was not statistically significant (p=0.4170). Conclusion: We showed that, mean LDH (IU/L) was significantly higher in Case Group compared to Control Group.