European Journal of Cardiovascular Medicine

: The aim of this study was to assess lipid profile among malaria-infected patients Material & Methods: An Observational Study on 168 patients in the Department of General Medicine, NMCH, Sasaram in between March 2021 to September 2022. Lab reports of malaria patients were obtained. Patient’s baseline demographic and clinical characteristics were recorded in a structured proforma. Estimations of malaria parasites based on thick and thin smear for parasite (PSMP) & RCT for MP was done. Blood samples were taken for estimation of lipid profile in addition to routine laboratory investigations. Lipid profile test was be done by ERBA EM-200 analyzer. Results: This study was concluded on 168 laboratory- confirmed cases of malaria patients of P. vivax (84) and Mixed malaria- P. falciparum+ P. vivax (84). There were 168 healthy volunteers taken as the control group. The mean ages of patients in P. vivax group were 26.20±13.80, Mixed Malaria group was 34.82±12.50, and the control group was 38.00±9.70 respectively. The sex distribution among cases & control (males-80% and females 20%). for total cholesterol, HDL and LDL were significantly lower in case group 95.21±22.24 mg/dl, 13.24±7.01 mg/dl and 64.85±16.50 mg/dl respectively than in control group of 182.73±17.14         mg/dl,         44.11±7.30,         and 112.38±17.37 mg/dl respectively (p <0.05). But, serum triglyceride and VLDL were significantly higher in case group 146.78±38.59 mg/dl and 29.35±7.27 mg/dl respectively than in control group 132.40±15.51 mg/dl and 24.68±3.68 mg/dl respectively (p <0.05). Conclusion: In conclusion, the characteristic pattern of derangements in lipid profile in malaria patients. Malaria parasites, both P. vivax and P. falciparum infections, cause derangements in lipid profile that are characterised by low serum total cholesterol, low HDL, low LDL and high triglyceride levels. The decrease in some of the lipids might lead to the onset of severe malarial infection