European Journal of Cardiovascular Medicine

Introduction: PONV is defined as nausea and/or vomiting occurring within 24 h after surgery. Post-operative nausea and vomiting (PONV) is a common and distressing complication after anaesthesia and surgery, with an incidence of approximately 30%. PONV is usually self-limiting and nonfatal but it is unpleasant and leads to considerable post-operative discomfort and dissatisfaction. Objectives: Efficacy of dextrose infusion before induction to prevent post-operative nausea vomiting and whether it is influenced by plasma osmolarity.  Materials and Methods: The present study was a prospective randomized double blinded clinical study. This Study was conducted from January 2019 to January 2020 at Department of Anaesthesiology, Bankura Sammilani Medical College and Hospital, Bankura, West Bengal. Result: Rapid infusion of 5%Dextrose may increase the blood sugar level to an unexpected level which was our concerned. But after completion of the study we found negligible amount of patients (13.3% at immediate post-operative period, 5.3% at 1st hour post-operative period, 2.6% at 2nd hour post-operative period) in Group D had capillary blood glucose level more than 180mg/dl which is the upper limit of target blood sugar level perioperatively.  Conclusion: From our study it was found that intra venous administration of Dextrose (5%) before induction of patient’s undergone laparoscopic cholecystectomy can reduce post-operative nausea and vomiting (PONV) significantly and even if PONV occurred the quantity of rescue antiemetic combat PONV also reduced significantly.