European Journal of Cardiovascular Medicine

Introduction: Cardiovascular disease is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD).  Objective: To study the cardiovascular events in chronic kidney disease patients and to correlate the events with various stages of CKD, events with the duration of CKD and to study the in-hospital mortality in them. Methods: This is a cross-sectional observational study conducted on stage 3 to 5 CKD patients at a tertiary care hospital. 106 patients are enrolled from March 2021 to September 2022 and evaluated for cardiovascular events. Baseline data, comorbidities and in hospital mortality are determined. They are correlated with the stage of CKD and duration of CKD.  Results: The mean age of the study population is 52.16± 13 years. 63.2% patients are males and 36.8% are females. 57.5% patients are in stage 5 CKD. 34% patients presented with cardiovascular events. The most frequent cardiovascular event is sudden cardiac death (10.3%) followed by acute decompensated heart failure (6.6%). In stage-5 CKD, 75% patients have cardiovascular events (p value <0.033). In patients with CKD duration >2 years, 50% have cardiovascular events (p value <0.00001). 13.2% is the in-hospital all-cause mortality and 78.5 % of mortality is attributable to cardiovascular events. Conclusion: Cardiovascular events increases as the stage and duration of CKD progresses. cardiovascular events are the major determinants of in-hospital mortality in chronic kidney disease patients.