European Journal of Cardiovascular Medicine

Introduction:  Introduction: Nerve Conduction Study (NCS) are most commonly used in neurophysiological laboratories not only for the understanding of normal peripheral nerve function and structure but also in relation to various diseases. Peripheral neuropathies are unfavorable consequences of radiation treatment. Tissue changes due to Radiation Exposure result in inflammation and fibrosis that affect the peripheral nerve and lead to peripheral neuropathies. Hence we have undertaken this study to observe effect of radiation exposure on peripheral nerve conduction study parameters in Radiologic Technologists of our institutions and compared the nerve conduction study with healthy individuals. Material and methods: Present study is a case control cross-sectional analytic prospective hospital-based study. In present study a sum of 60 individuals were selected, of which 30 were Radio-logic Technologists (study group/cases) who had a history of occupational exposure to ionizing radiations and 30 were age and sex matched normal healthy individuals (controls). Motor Nerve conduction study (MNCS) parameters for sensory and motor were recorded in Median, Ulnar and Radial nerves on both right and left Upper extremities and data was recorded.We found that the nerve conduction velocities of all the motor and sensory nerves were significantly reduced in radiologic technologists compared to healthy subjects.  Results and discussion :We also found reduced CMAP amplitude (significant in Ulnar, and Radial) and SNAP amplitude (significant in Median, Ulnar and Radial nerves) along with prolonged motor distal latencies (significant in Median, Ulnar and Tibial nerves) and sensory distal latencies (significant in Median, Ulnar and Radial nerves) among radiological technologists compared to healthy individuals. Conclusion: Present study depicting that ionizing radiations are harmful to all the body tissues including the peripheral nerves. Radiations appear to cause both demyelination and axonal loss.