European Journal of Cardiovascular Medicine

Background: “Non Alcoholic Fatty Liver Disease” is one of the most quotidian liver diseases in the entire world. The risk factors for developing “Non Alcoholic Steato-Hepatitis” or (NASH) include – 1) Obesity, especially Central Adiposity, 2) Impaired Glucose tolerance,3) ‘Type 2 diabetes mellitus’ (T2DM), and 4) Dyslipidemia. Material And Methods: A total of 65 NAFLD patients, both male and female, were included in the research study. ‘Type 2 diabetes mellitus’ diagnosis was made according to ADA criteria which includes – (1) symptoms of diabetes mellitus plus random blood glucose concentration more than equal to 11.1mmol/L(200mg/dl); (2) Fasting blood(plasma) glucose more than 7.0mmol/L(126mg/dl); (3) Two hour plasma glucose more than equal to 11.1 mmol/L(200mg/dl) on oral glucose tolerance test (OGTT). Results: This study shows Association of and PP blood sugar levels with hypertension and obesity. It shows mean ± SD (175.57±72.50) of fasting blood sugar in NAFLD hypertensive subgroup was found to be higher as compared to NAFLD without hypertension mean±SD (133.43±68.06). This was statistically significant(p=.020).Mean±SD(292±107.62) of Post Prandial blood sugar in NAFLD-hypertension subgroup was found to be higher than the Post Parandial blood sugar of NAFLD without hypertension & this was statistically significant(p=.04). The mean±SD(175.12±77.50) of fasting blood sugar of Obesity fasting subgroup of NAFLD were higher as compared to mean±SD of those without obesity(138.0±63.78). This was found to be statistically significant. Conclusion: The present study concludes that higher fasting and postprandial glucose level were significantly associated to NAFLD in hypertensive patients compared to non hypertensive NAFLD patients. Also significant higher fasting glucose levels were associated with obese patients having NAFLD compared to non obese patients having NAFLD. Timely assessment and analysis of NAFLD at a mild stage or at a moderate stage with appropriate and adequate lifestyle changes of the patients such as (1) physical activities and (2) proper diet could thus indirectly prevent the occurrence of pathological states including ‘type 2 diabetes mellitus’, obesity and metabolic syndrome. Future research with bigger study sample are needed for more concrete and decisive outcomes.