European Journal of Cardiovascular Medicine

Objective:  The aim of this study was to compare total antioxidant Levels in Patients with Type 2 Diabetes Mellitus. Materials And Method: A case control study was undertaken in a medical care hospital to find out the antioxidant status in patients with Type 2 Diabetes Mellitus compared to normal healthy subjects, significance of estimation of serum vitamin C and vitamin E levels as indicators of antioxidant status and development of diabetic complications due to their deficiency.  The fasting Blood sugar (FBS), HbA1C, Vitamin C, Vitamin E, Serum total cholesterol, serum triglyceride (TGL), and serum high density lipoprotein (HDL) were estimated. Results: The level of antioxidants (vitamin C and vitamin E) is decreased in Type 2 Diabetes Mellitus which is more in case of diabetes with complications. Antioxidant status can be used as an indicator of severity complication and duration of Type 2 Diabetes Mellitus. Conclusion:  Diabetic patients also have a well documented defect in antioxidant protection which have been studied by various research workers, and in the present study also it is seen that the level of antioxidants in the complicated cases of Type 2 Diabetes Mellitus are remarkably lowered when compared to the Type 2 Diabetes Mellitus without complications