European Journal of Cardiovascular Medicine

Introduction: Corona virus disease 2019 (COVID-19) is highly contagious and has great transmission rate. Growing amounts of research are showing how inflammation affects COVID-19 patients; illness development and mortality. An important aspect of COVID-19 pathogenesis is inflammation. Aim: To study the association of inflammatory markers in COVID-19 patients with and without comorbidity. Materials and Methods: The study was conducted in the Department of Physiology and Department of Respiratory Medicine, SGRRIMHS, Dehradun, prospectively in COVID-19 patients who were admitted to the Department of Respiratory Medicine, Shri Mahant Indiresh Hospital, SGRRIMHS, Dehradun, COVID ward with positive RT PCR (real-time reverse-transcriptase-polymerase-chain-reaction) test. Blood samples were taken at the time of admission for laboratory assessments of inflammatory markers i.e. CRP, Ferritin, LDH, D-Dimer, and Procalcitonin. Results: CRP, Ferritin, D-Dimer, and LDH levels were raised in all Covid patients whereas the levels of Procalcitonin were within the normal range. The levels of CRP, Ferritin, D-Dimer, and LDH levels were raised more among Covid patients with comorbidity as compared to Covid patients without comorbidity. Serum Ferritin and LDH levels were statistically significant among patients with comorbidity [p < 0.05]. Conclusion: CRP, Ferritin, D-Dimer and LDH were raised among Covid patients with comorbidity and the levels of Ferritin and LDH were statistically significant among Covid patients with comorbidity.