European Journal of Cardiovascular Medicine

Introduction: Drug therapy for Crohn’s disease and ulcerative colitis is based on anti‐inflammatory and immunomodulating drugs, nutritional support and surgical resection. 5-Aminosalicylates are extensively prescribed for the treatment of ulcerative colitis but have a wide range of described adverse effects. Aims: To record the probable adverse drug reactions of pharmacotherapeutics commonly prescribed in gastroenterology OPD and to assess the causality and severity of adverse events. Materials and Methods: This observational cross-sectional study was conducted Gastroenterology OPD, RG Kar Medical College, and Kolkata. Adult patients aged less than 65 completed years and participant must have a diagnosis of Ulcerative colitis / Crohn’s Disease were included in this study. Result: We examined that in without Smoker, 12 (15.2%) patients had Pedal oedema and in with Smoker, 1 (9.1%) patient had Pedal oedema which was not statistically significant (p=0.5898).In without Alcoholic, 11 (12.9%) patients had Pedal oedema and in with Alcoholic, 2 (40.0%) patients had Pedal oedema which was not statistically significant (p=0.0943). Conclusion: It was found that Psoriasis was significantly higher in non-diabetic patients compared to diabetic patients and Headache, Arthritis, Pain Abdomen were not significantly associated with diabetic patients but Skin rash was more in non- diabetic patients.