European Journal of Cardiovascular Medicine

Purpose: The purpose of this study was to examine how the SARS-CoV-2 infection affects antenatal women and newborn babies in terms of symptoms, complications, and outcomes. Methods: A total of 128 antenatal women were included in this prospective single-center observational study. The present study was conducted in a tertiary-level public hospital in Kerala. The presence of SARS-CoV-2 was detected by running a real-time PCR using the extracted RNA using an appropriate PCR kit (SeegenAllplexTM 2019-nCoV Assay). Result: Out of 128 COVID-19-positive antenatal women, RT-PCR was positive for 57.8% of them, followed by antigen positive for 34.4% and TrueNat for 7.1%. The Mean ±SD duration of COVID positivity from delivery was 8.45±5.1 days and the Mean ±SD CRP was 3.15±6.2 mg/dl, Mean ±SD FERRITIN was 61.8±98.2 mg/l and the Mean ±SD D DIMER was 2.09±1.4 mg/l. Seven study subjects were transferred to the intensive care unit (ICU), 5 were given oxygen support, 3 were given NIV assistance with oxygen, and one was transferred on mechanical ventilation due to a severe complication. Out of 128 COVID-positive study subjects, the majority of them didn’t have any post-partum complications. 19 study subjects experienced complications such as PPH (10 study subjects), sepsis, and maternal near-miss (4 study subjects), and one study subject died due to thromboembolism. Conclusion: The study demonstrated that LSCS was more in COVID pregnant women. However, the majority of the COVID-positive pregnant women didn’t require ICU admission. Further, the study found that the majority of the neonates were COVID-negative and healthy.