European Journal of Cardiovascular Medicine

Background: The hospitals have high burden of nosocomial infections,usually caused by multi drug resistant nosocomial organisms.Amongst them Pseudomonas aeruginosa is one of the most difficult pathogens, an epitome of opportunistic nosocomial infections and causes severe and life-threatening infections.This is a compelling problem in hospital settings and needs to have studies on antimicrobial susceptibility pattern to guide the hospital policy on the appropriate use of antibiotics.= Material and methods: A cross-sectional studyat a tertiary care hospital, RIMS, Ranchi, was conducted from October 2017 to September 2018.Phenotypically identified by standard methods (biochemical tests). Antibiotic susceptibility test was carried out by Kirby-Bauer disc diffusion method as per Clinical Laboratory Standards Institute guidelines (CLSI guidelines). Results: A total of 107 samples were processed. Majority of samples were from IPD (69.15%). Among 107 patients, there were 75.70% males and 24.29% females. About 23% of the patients were >50 years of age. The samples mainly comprised of pus (50.46%) followed by urine (30.84 %).Maximum number of pus samples were obtained from general surgery, neurosurgery, orthopaedics, and ENT inpatients.Imipenem (75.70%), Piperacillin-Tazobactam (74.77%), Meropenem (70.09%) in the decreasing order were the most sensitive against P. aeruginosa strains.