European Journal of Cardiovascular Medicine

Background:  Epilepsy is one of the common chronic conditions affecting women of reproductive age. The rates of maternal death are ten-fold higher in women with epilepsy than those without the condition. Care of women with epilepsy continues to be fragmented, with few units providing joint obstetric-epilepsy care. Objectives: To determine the obstetric and neonatal outcome of pregnancy in women with epilepsy. Material & Methods:  Study Design: Hospital based prospective observational study. Study area: Department of Obstetrics & Gynecology, Mayo institute of Medical Sciences, Barabanki, Uttar Pradesh. Study Period:  June 2022 to May 2023.  Study population:  Pregnant women with epilepsy attending the antenatal clinic at Mayo institute of Medical Sciences, Barabanki, Uttar Pradesh. Sample size:  The study included a target number of 200 subjects with 50 as cases and 150 as controls. Sampling Technique:  Simple Random technique. Results: The percentage of IUD was 6% in cases and 14% in controls, the difference is not statistically significant. The percentage of antepartum hemorrhage in cases was 4%, while it was 3.33% in controls. The difference is not significant statistically. The percentage of abortions in cases was 4% and in controls it was 4%. The difference is not significant statistically. Conclusion: The present study provides reassurance to women with epilepsy that, epilepsy in pregnancy in the majority of women is uneventful. AED use during pregnancy is generally not associated with adverse maternal and fetal or neonatal outcomes, although it is important to be aware that AEDs differ in their teratogenic potential.