European Journal of Cardiovascular Medicine

Diagnosis of extrapulmonary tuberculosis is challenging due to pauci bacillary disease and is mostly multidimensional involving judgmental assessment of clinical features and disease-related structural radiological changes. The study was undertaken to assess the utility of CBNAAT in field conditions in evaluatingboth Pulmonary and extrapulmonary tuberculosis patients. Methodology: This study was a prospective Observational study conducted in a tertiary care hospital in Jamnagar, West Gujarat. Among 125 extra-pulmonary patients, 34.4% were 20-39 years and 68(54.4) were males, and 85(68) were newly diagnosed. In pulmonary 36.9% were 20-39 Years,51(78.4) were males and 45(69) were newly diagnosed. Results: Out of 125 extrapulmonary TB patients, CBNAAT detected MTB in 50%,44.44%,34.71%,15%,10%,10%,0.0%,and0.0% respectively in articular, pus, lymph node, CSF, pleuralfluids, gastric fluids, pericardialand urinary TB. CBNAATMTB detection was 66.67%, 50% ,50%,0.0%,33.33%, and 0.0%in pus aspirated from psoasabscess, breastabscess ,chest walls welling, splenic abscess, gluteal abscess, and occipitals welling respectively. Conclusion: The diagnostic efficacy of CBNAAT MTB was greater in pulmonary TB than in extrapulmonary TB. The highest diagnostic yield of CBNAAT was found in non-lymph nodalpurulentaspirate, most forpsoas abscessaspirate. The lowest diagnostic efficacy of CBNAAT inextrapulmonary TB was forurinary and peritoneal fluid samples. CBNAAT was found high diagnostic yield tool for cases of necrotic lymphadenopathy, psoasabscess, and articular disease with fusion