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Research Article | Volume 13 Issue:2 (, 2023) | Pages 1773 - 1782
The Application of the Neutrophil-Lymphocyte Ratio as a Diagnostic Tool for the Early Detection of Sepsis- A Case Control Study
Under a Creative Commons license
Open Access
DOI : 10.5083/ejcm
Published
June 26, 2023
Abstract

Background: Sepsis, a potentially fatal medical condition, typically prompts patients to seek initial medical attention in the emergency department (ED). However, the timely detection of sepsis in this setting is often difficult due to the absence of a reliable diagnostic framework. Methods: The current study pertains to a case-control study involving adult patients who have been admitted to an intensive care unit. The study included individuals who were admitted to the hospital with sepsis as the primary cause and had previously undergone a complete blood count examination. These individuals were classified as case patients.  Results: The identification of risk factors for sepsis includes a neutrophil-lymphocyte ratio exceeding 5.0, leukocyte count surpassing 12,000mm3/mL, and band neutrophil percentage exceeding 10%. Nevertheless, it is worth noting that only the SAPS 3 and SOFA score demonstrated a significant association with patient mortality. Conclusion: The neutrophil- lymphocyte ratio and band neutrophils in combination with other parameters may be markers for the early detection of sepsis in intensive care units.

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