European Journal of Cardiovascular Medicine

Background: Diabetes mellitus is the most common endocrine disorder. It is a state of persistent hyperglycemia secondary to defects in insulin secretion, insulin action, or both. The development of Diabetes involves several pathogenic processes ranging from autoimmune destruction of the β cells of the pancreas resulting in absolute insulin deficiency, to other abnormalities that result in insulin resistance. The purpose of this study helps in recognition of the interdependent relationship between thyroid disease and diabetes and guides clinicians on the optimal management of both these conditions. Methods: This is a hospital based prospective study of 100 patients with type 2 diabetes mellitus admitted in the Department of General Medicine, SVRR Govt. General Hospital S.V.Medical college, Tirupati. Fasting and postprandial blood sugars HbA1C thyroid profile which includes t3, t4, TSH levels were measured. Results: Out of 100 patients, 77.0% of patients had normal thyroid function (i.e. Euthyroid). 16.0% of patients had subclinical hypothyroidism. 6.0% of patients had Hypothyroidism and 1% of patients had Hyperthyroidism. The mean ofHbA1C (1%) in patients with thyroid dysfunction was 9.00 (i.e. 1.74). The mean(SD) of HbA1C(1%) in patients with normal thyroid function was 8.78 (i.e. 1.52). This was statistically insignificant (P value 0.441). Conclusion: There was no significant difference between Euthyroid patients and patients with thyroid dysfunction in terms of duration of Diabetes and HbA1Cin the present study.