European Journal of Cardiovascular Medicine

Introduction: Early detection and treatment of dysglycemia including diabetes and pre- diabetes is demonstrated to improve disease outcomes and prevent complications. Material and Methods: This is a Prospective observational cohort study, A total of 240 patients from Outpatient department (OPD) and Indoor patient (IPD) department of Medicine, Dr. Baba Saheb Ambedkar Medical college and Hospital, New Delh. Anthropomorphic measurements, demographic and clinical information were taken, and blood pressure was measured. Fasting blood sample was obtained for the measurement of plasma glucose (FPG), glycated hemoglobin (HbA1C), and lipid profile. Plasma glucose was estimated 1 hr after the ingestion of 50 g glucose (1h-OGTT). Prediabetes and dyslipidemia were defined according to international guidelines.  Results: A total of 240 individuals were included with a mean age (±SD) of 53.020+-16.5 years, mean BMI of 24.555±12.8 kg/m2. The initial lipid parameters of the participants were analyzed. It was found that 77% of the individuals had baseline total cholesterol levels within the normal range, with a mean value of 170.8mg/dl. Additionally, 85% of the participants had baseline HDL levels within the normal range, with a mean value of 41.9mg/dl. At baseline, 50% of the participants had normal LDL levels, while the other 50% had abnormal LDL levels, with a mean value of 100.6mg/dl. Furthermore, 94% of the participants had baseline VLDL levels, with a mean value of 22.2mg/dl. Lastly, 89.5% of the participants had baseline TG levels within the normal range, with a mean value of 100.75mg/dl. Conclusion: Even though high LDL-C is associated with prediabetes, a recommendation for universal screening of prediabetes patients requires further cohort studies.